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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APLP2 All Species: 21.52
Human Site: Y721 Identified Species: 67.62
UniProt: Q06481 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q06481 NP_001135748.1 763 86956 Y721 V M L R K R Q Y G T I S H G I
Chimpanzee Pan troglodytes Q5IS80 770 86953 Y728 V M L K K K Q Y T S I H H G V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536530 763 86644 Y721 V M L R K R Q Y G T I S H G I
Cat Felis silvestris
Mouse Mus musculus Q06335 695 78926 Y653 V M L R K R Q Y G T I S H G I
Rat Rattus norvegicus P15943 765 86864 Y723 V M L R K R Q Y G T I S H G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres O93279 737 82838 Y695 V M L R K K Q Y T S I H H G V
Fruit Fly Dros. melanogaster P14599 887 98314 G846 S R S P H A Q G F I E V D Q N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10651 686 79416 R645 A F A I T N A R R R R A M R G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.3 N.A. 94.6 N.A. 83 92.9 N.A. N.A. N.A. N.A. N.A. 47.5 26.4 N.A. 24.3 N.A.
Protein Similarity: 100 66.8 N.A. 97.1 N.A. 87.5 95.9 N.A. N.A. N.A. N.A. N.A. 64.2 43.8 N.A. 44.5 N.A.
P-Site Identity: 100 60 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. 66.6 6.6 N.A. 0 N.A.
P-Site Similarity: 100 86.6 N.A. 100 N.A. 100 100 N.A. N.A. N.A. N.A. N.A. 86.6 6.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 0 13 13 0 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % E
% Phe: 0 13 0 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 50 0 0 0 0 75 13 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 25 75 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 13 75 0 0 0 50 % I
% Lys: 0 0 0 13 75 25 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 75 0 0 0 0 0 0 0 0 0 0 13 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 13 % N
% Pro: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 88 0 0 0 0 0 0 13 0 % Q
% Arg: 0 13 0 63 0 50 0 13 13 13 13 0 0 13 0 % R
% Ser: 13 0 13 0 0 0 0 0 0 25 0 50 0 0 0 % S
% Thr: 0 0 0 0 13 0 0 0 25 50 0 0 0 0 0 % T
% Val: 75 0 0 0 0 0 0 0 0 0 0 13 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _